Helmholtz Centre for Infection Research (HZI)

The Helmholtz Centre for Infection Research (HZI) in Braunschweig is a publicly funded research centre with more than 800 employees and an annual budget of approximately 90 million Euros as well as an additional approximately 19 million Euros of external funds from national and international support programmes, and industry. The focus of its activities lies on the field of infection. The mission of the HZI is to rise to the societal challenges of infectious diseases by investigating their fundamental pathogenesis mechanisms, with the aim of deriving innovative approaches for their prevention, diagnosis and therapy. The HZI is also member of the German Centre for Infection Research (35 research institutions located at seven sites), being the managing office located at the HZI campus.

Main roles in project
The HZI will be responsible for the overall coordination of the project. The HZI will also contribute to the scientific tasks by providing expertise and technologies in the fields of vaccinology, immunology and adjuvants. More specifically, the HZI will evaluate the immunogenicity of the Traspain-based vaccine against T. cruzi in a preclinical setting in the model organism mouse, and evaluate the immunogenicity of the vaccine, in terms of both innate and adaptive immune responses, in the clinical trial vaccinees.

Contact: Prof. Carlos A. Guzmán